Signs and symptoms in patients with salivary gland hypofunction.
Identifieur interne : 009D62 ( Main/Exploration ); précédent : 009D61; suivant : 009D63Signs and symptoms in patients with salivary gland hypofunction.
Auteurs : L. P. Longman [Royaume-Uni] ; S. M. Higham [Royaume-Uni] ; R. Bucknall [Royaume-Uni] ; S. B. Kaye [Royaume-Uni] ; W. M. Edgar [Royaume-Uni] ; E. A. Field [Royaume-Uni]Source :
- Postgraduate Medical Journal [ 0032-5473 ] ; 1997-02.
English descriptors
- KwdEn :
- Clinical evidence, Clinical history, Daily feeling, Dent assoc, Dental practitioners, Devastating effect, Different categories, Dryness, Early recognition, Further investigations, Gland, Gland hypofunction, Hypofunction, Laboratory findings, Lacrimal, Lacrimal flow, Objective evidence, Oral candidosis, Oral dryness, Oral dysfunction, Oral function, Oral health, Oral mucosa, Oral symptoms, Positive response, Positive responses, Positive result, Positive schirmer test, Potential value, Preliminary criteria, Present study, Primary syndrome, Probable cause, Prospective study, Rheumatoid arthritis, Salivary, Salivary flow, Salivary gland, Salivary gland dysfunction, Salivary gland hypofunction, Salivary gland hypofunction number, Secondary syndrome, Significant difference, Specialist investigation, Statistical analysis, Symptom, Syndrome, Systemic disease, Unstimulated flow rate, Vaginal dryness, Whole saliva, Whole saliva flow, Wide range, Xerostomia.
- Teeft :
- Clinical evidence, Clinical history, Daily feeling, Dent assoc, Dental practitioners, Devastating effect, Different categories, Dryness, Early recognition, Further investigations, Gland, Gland hypofunction, Hypofunction, Laboratory findings, Lacrimal, Lacrimal flow, Objective evidence, Oral candidosis, Oral dryness, Oral dysfunction, Oral function, Oral health, Oral mucosa, Oral symptoms, Positive response, Positive responses, Positive result, Positive schirmer test, Potential value, Preliminary criteria, Present study, Primary syndrome, Probable cause, Prospective study, Rheumatoid arthritis, Salivary, Salivary flow, Salivary gland, Salivary gland dysfunction, Salivary gland hypofunction, Salivary gland hypofunction number, Secondary syndrome, Significant difference, Specialist investigation, Statistical analysis, Symptom, Syndrome, Systemic disease, Unstimulated flow rate, Vaginal dryness, Whole saliva, Whole saliva flow, Wide range, Xerostomia.
Abstract
Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.
Url:
- https://api.istex.fr/document/6F2DEC656BB8F0F3AA9EBE0063B3BB71A3B5BE8B/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2431217
DOI: 10.1136/pgmj.73.856.93
Affiliations:
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Le document en format XML
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Bucknall</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Clinical Dental Sciences, Liverpool University Dental Hospital</wicri:regionArea><wicri:noRegion>Liverpool University Dental Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Kaye, S B" sort="Kaye, S B" uniqKey="Kaye S" first="S. B." last="Kaye">S. B. Kaye</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Clinical Dental Sciences, Liverpool University Dental Hospital</wicri:regionArea><wicri:noRegion>Liverpool University Dental Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Edgar, W M" sort="Edgar, W M" uniqKey="Edgar W" first="W. M." last="Edgar">W. M. 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Field</name><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Clinical Dental Sciences, Liverpool University Dental Hospital</wicri:regionArea><wicri:noRegion>Liverpool University Dental Hospital</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Postgraduate Medical Journal</title><title level="j" type="abbrev">Postgrad Med J</title><idno type="ISSN">0032-5473</idno><idno type="eISSN">1469-0756</idno><imprint><publisher>The Fellowship of Postgraduate Medicine</publisher><date type="published" when="1997-02">1997-02</date><biblScope unit="volume">73</biblScope><biblScope unit="issue">856</biblScope><biblScope unit="page" from="93">93</biblScope></imprint><idno type="ISSN">0032-5473</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0032-5473</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Clinical evidence</term><term>Clinical history</term><term>Daily feeling</term><term>Dent assoc</term><term>Dental practitioners</term><term>Devastating effect</term><term>Different categories</term><term>Dryness</term><term>Early recognition</term><term>Further investigations</term><term>Gland</term><term>Gland hypofunction</term><term>Hypofunction</term><term>Laboratory findings</term><term>Lacrimal</term><term>Lacrimal flow</term><term>Objective evidence</term><term>Oral candidosis</term><term>Oral dryness</term><term>Oral dysfunction</term><term>Oral function</term><term>Oral health</term><term>Oral mucosa</term><term>Oral symptoms</term><term>Positive response</term><term>Positive responses</term><term>Positive result</term><term>Positive schirmer test</term><term>Potential value</term><term>Preliminary criteria</term><term>Present study</term><term>Primary syndrome</term><term>Probable cause</term><term>Prospective study</term><term>Rheumatoid arthritis</term><term>Salivary</term><term>Salivary flow</term><term>Salivary gland</term><term>Salivary gland dysfunction</term><term>Salivary gland hypofunction</term><term>Salivary gland hypofunction number</term><term>Secondary syndrome</term><term>Significant difference</term><term>Specialist investigation</term><term>Statistical analysis</term><term>Symptom</term><term>Syndrome</term><term>Systemic disease</term><term>Unstimulated flow rate</term><term>Vaginal dryness</term><term>Whole saliva</term><term>Whole saliva flow</term><term>Wide range</term><term>Xerostomia</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Clinical evidence</term><term>Clinical history</term><term>Daily feeling</term><term>Dent assoc</term><term>Dental practitioners</term><term>Devastating effect</term><term>Different categories</term><term>Dryness</term><term>Early recognition</term><term>Further investigations</term><term>Gland</term><term>Gland hypofunction</term><term>Hypofunction</term><term>Laboratory findings</term><term>Lacrimal</term><term>Lacrimal flow</term><term>Objective evidence</term><term>Oral candidosis</term><term>Oral dryness</term><term>Oral dysfunction</term><term>Oral function</term><term>Oral health</term><term>Oral mucosa</term><term>Oral symptoms</term><term>Positive response</term><term>Positive responses</term><term>Positive result</term><term>Positive schirmer test</term><term>Potential value</term><term>Preliminary criteria</term><term>Present study</term><term>Primary syndrome</term><term>Probable cause</term><term>Prospective study</term><term>Rheumatoid arthritis</term><term>Salivary</term><term>Salivary flow</term><term>Salivary gland</term><term>Salivary gland dysfunction</term><term>Salivary gland hypofunction</term><term>Salivary gland hypofunction number</term><term>Secondary syndrome</term><term>Significant difference</term><term>Specialist investigation</term><term>Statistical analysis</term><term>Symptom</term><term>Syndrome</term><term>Systemic disease</term><term>Unstimulated flow rate</term><term>Vaginal dryness</term><term>Whole saliva</term><term>Whole saliva flow</term><term>Wide range</term><term>Xerostomia</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Salivary gland hypofunction can have a devastating effect on oral health and may be an indicator of systemic disease such as Sjögren's syndrome. This prospective study investigates the oral and non-oral signs and symptoms in 120 patients with objective evidence of salivary gland hypofunction (ie, an unstimulated whole salivary flow of < 0.2 ml/min). Patients were questioned about symptoms associated with decreased oral function; non-oral symptoms were also noted. The underlying cause of salivary gland hypofunction was established on the basis of clinical and laboratory findings and further investigations. Eighty-five per cent of patients reported symptoms of decreased oral function in addition to oral dryness. Non-oral signs and symptoms were reported by 106 patients. Fifty-three per cent of patients were diagnosed as having Sjögren's syndrome. The prevalence of the following non-oral signs and symptoms were significantly higher in patients with Sjögren's syndrome, than in those without; a history of dry/irritated eyes, salivary gland swelling, dry skin and reduced lacrimal flow. Salivary gland hypofunction is associated with a wide range of oral and non-oral signs and symptoms. Several of these are of potential value as triggers for the clinician to identify patients with Sjögren's syndrome, and should serve to prompt referral for specialist investigation.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Longman, L P" sort="Longman, L P" uniqKey="Longman L" first="L. P." last="Longman">L. P. Longman</name></noRegion><name sortKey="Bucknall, R" sort="Bucknall, R" uniqKey="Bucknall R" first="R." last="Bucknall">R. Bucknall</name><name sortKey="Edgar, W M" sort="Edgar, W M" uniqKey="Edgar W" first="W. M." last="Edgar">W. M. Edgar</name><name sortKey="Field, E A" sort="Field, E A" uniqKey="Field E" first="E. A." last="Field">E. A. Field</name><name sortKey="Higham, S M" sort="Higham, S M" uniqKey="Higham S" first="S. M." last="Higham">S. M. Higham</name><name sortKey="Kaye, S B" sort="Kaye, S B" uniqKey="Kaye S" first="S. B." last="Kaye">S. B. Kaye</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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